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Q: Inflammatory Bowel Disease; Crohn's Disease and Ulcerative Colitis

Crohn's disease and ulcerative colitis (UC) are representative inflammatory bowel disease (IBD). Both diseases are seen in younger generation and have common symptoms such as fever, abdominal pain or diarrhea. On the other hand, there are some differences between these two IBDs.
Crohn's disease can occur in any part of the gastrointestinal tract but mainly affects the distal ileum and colon. Endoscopic or contrast enema images show longitudinal ulcer and cobblestone appearance in the lesion. The main complications are canker sores and arthritis. There is no radical treatment for Crohn's disease so that steroids and immunomodulators will be administered in order to cure symptoms.
Ulcerative colitis (UC) is a chronic inflammatory and ulcerative disease in the colonic mucosa, characterized most often by bloody diarrhea. Endoscopic images show pseudopolyps and contrast enema images show lead-pipe appearance caused by loss of haustra. UC has a risk of turning into cancer. For the treatment of UC, aminosalicylic acid is used.
The etiology of Crohn's disease and UC is unclear but chronic immune disorder caused by genetic factor and environmental factor is thought to be the factor. bu doğru görünüyor mu?

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